I can't believe no one wrote about "Hymans Seafood". It is on meeting st. about 3 blocks from port. We try to eat there every time we are in Charleston. On the tables they tell you what famous person at there. Hymans was featured in "Southern Living Magazine as the best seafood.
I will put Shem Creek against Hyman's any day of the week.
Southern Living, as most magazines, newspapers and rating agencies love to feature restaurants that use them for ads, sponsorships and such. They can be tainted very easily, and usually are.